| All-Time | Active | Coach | Record ('08) | Win% | Years | Seasons | Wins Per Season | School/Area |
| 1 | 1 | John McKissick | 594-143-13 (8-5-0) | 80.067 | 1952-current | 60 | 9.900 | Summerville - |
| 2 | 2 | John T. Curtis | 506-54-6 (14-0-0) | 89.929 | 1969-current | 43 | 11.767 | John Curtis - |
| 3 | 3 | Larry Campbell | 459-79-3 (12-1-0) | 85.120 | 1972-current | 40 | 11.475 | Lincoln County - |
| 4 | 4 | G. A. Moore | 431-98-9 (4-7-0) | 80.948 | 1962-04, 09-current | 48 | 8.979 | Aubrey Pilot Point - |
| 5 | 5 | Mike Smith | 428-69-2 (9-3-0) | 85.972 | 1971-current | 41 | 10.439 | Hampton - |
| 6 | 6 | Corky Rogers | 414-71-1 (16-1-0) | 85.288 | 1968-current | 44 | 9.409 | The Bolles School, Jacksonville FL - |
| 7 | | George Curry | 413-91-5 | 81.631 | 1967-08 | 42 | 9.833 | Wyoming Valley West, Berwick - |
| 8 | | Pete Atkins | 405-60-4 | 86.780 | 1951-94 | 44 | 9.205 | Missouri - |
| 9 | 7 | Al Fracassa | 404-115-7 (10-4-0) | 77.471 | 1963-current | 49 | 8.245 | Bloomfield Hills Brother Rice - |
| 10 | | Gordon Wood | 396-91-15 | 80.378 | 1940-85 | 46 | 8.609 | Texas - |
| 11 | 8 | Dick Tighe | 390-153-8 (9-2-0) | 71.506 | 1954-current | 58 | 6.724 | St. Edmond, Fort Dodge - |
| 12 | 9 | John Herrington | 386-87-1 (10-1-0) | 81.540 | 1970-current | 42 | 9.190 | Farmington Hill, Harrison MI - |
| 13 | 10 | Bob Ladouceur | 385-24-3 (13-1-0) | 93.811 | 1979-current | 35 | 11.000 | Concord De La Salle, CA - |
| 14 | | Willie Varner | 383-132-10 | 73.905 | 1954-96 | 43 | 8.907 | Woodruff - |
| 15 | 11 | Bob Lutz | 381-93-5 (7-5-0) | 80.063 | 1969-05, 07-current | 42 | 9.071 | Ironton Ironton St. Joe - |
| 15 | | Ron Holtman | 381-103-8 | 78.252 | 1955-04 | 50 | 7.620 | Alton Marquette IL - |
| 17 | 12 | Robert Hyland | 374-104-2 (14-0-0) | 78.125 | 1971-current | 41 | 9.122 | Fond du lac St Mary's Springs WI - |
| 18 | 13 | Larry (Bud) Wright | 371-161-2 (10-4-0) | 69.663 | 1968-current | | | Sheridan IN - |
| 18 | | Joe Bradshaw | 371-120-4 | 75.354 | 1962-05 | 44 | 8.432 | Aliceville, AL - |
| 20 | | Jerry Brewer | 368-105-2 | 77.684 | 1960-02 | 43 | 8.558 | Jasper - |
| 21 | | Frank McClellan | 367-77-4 | 82.366 | 1968-05 | 38 | 9.658 | Barton - |
| 22 | | Red Franklin | 366-76-8 | 82.222 | 1924-58 | 35 | 10.457 | Haynesville - |
| 23 | 14 | Curt Bladt | 364-40-0 (9-4-0) | 90.099 | 1978-current | 35 | 10.400 | Harlan IA - |
| 23 | | Howie Vogts | 364-124-10 | 74.096 | 1953-65, 67-09 | 55 | 6.618 | Bethpage NY - Deceased 2010 |
| 25 | | Elbert Wright | 361-126-17 | 73.313 | 1954-92 1994-99 | 45 | 8.022 | Texas - |
| 25 | 15 | Marijon Ancich | 361-137-4 (7-3-0) | 72.311 | 1961-05, 2009- | 45 | 8.022 | St. Paul CA Santa Fe Springs - |
| 25 | | Warren Wolf | 361-121-11 | 74.341 | 1958-08 | 51 | 7.078 | Brick - |
| 28 | | Terry Malone | 360-117-8 | 75.052 | 1956-03 | 48 | 7.500 | Hamilton Badin - |
| 29 | 16 | Jerry Pezzetti | 357-140-1 (11-2-0) | 71.787 | 1968-current | 44 | 8.114 | Ankeny IA Mechler-Dallas, Murray, IA - |
| 29 | 16 | Jack Henzes | 357-151-8 (10-1-0) | 69.961 | 1960-current | 51 | 7.000 | Dunmore PA Wyoming Area - Coach at Dunmore since 1971 - Inducted into NHSACA Hall of Fame in 2009 |
| 31 | | Carlton Flatt | 354-68-1 | 83.806 | 1971-98 2002-06 | 33 | 10.727 | Brentwood Academy - |
| 31 | 18 | Jim Render | 354-116-7 (11-2-0) | 74.948 | 1970-current | 40 | 8.850 | Upper St Clair Uniontown PA, Carroliton OH - |
| 33 | | Robert Davis | 353-73-1 | 82.787 | 1973-08 | 36 | 9.806 | WarnerRobins, Westside Macon - |
| 34 | 19 | Mike Boyd | 352-113-1 (4-5-0) | 75.644 | 1965-68, 70-current | 45 | 7.822 | Waterford Lady of the Lakes - |
| 35 | | Duane Twait | 350-64-3 | 84.293 | 1964-02 | 39 | 8.974 | Emmetsburg IA - |
| 35 | | Dick Basham | 350-87-0 | 80.092 | 1970-09 | 40 | 8.750 | Milwaukee Marquette, WI - |
| 37 | | Dan Pitts | 346-109-4 | 75.817 | 1959-97 | 39 | 8.872 | MaryPersons - Retired 1997 |
| 37 | | Pinky Babb | 346-86-24 | 78.509 | 1935-81 | 47 | 7.362 | Greenwood SC - |
| 39 | | Bob Schneider | 345-183-2 | 65.283 | 1966-09 | 43 | 8.023 | Newport Central Catholic KY - Retired January 2010 |
| 39 | | Jim Drewry | 345-158-5 | 68.406 | 1958-59, 1965-86, 1989-09 | 44 | 7.841 | Booneville MS - Retired after 2009 |
| 41 | | Tom Jaworski | 343-92-0 | 78.851 | 1972-10 | 38 | 9.026 | Creighton Prep - Retired after 2010 season |
| 42 | | Rod Wotton | 342-94-3 | 78.246 | 1963-10 | 46 | 7.435 | Aquinas, Dover NH - |
| 43 | 20 | Frank Pazzaglia | 340-136-8 (6-5-0) | 71.074 | 1969-current | 43 | 7.907 | Mid Valley, PA - |
| 44 | | Herb Meyer | 338-150-14 | 68.725 | 1959-03 | 45 | 7.511 | Oceanside CA - |
| 44 | 21 | Tom Stone | 338-97-1 (5-5-0) | 77.638 | 1967-current | 45 | 7.511 | Packwood Pekin, IA - |
| 46 | | Chris Geesman | 337-66-3 | 83.374 | 1965-02 | 38 | 8.868 | Mishawaka Penn IN - |
| 47 | | Edward Buller | 335-78-7 | 80.595 | 1940-84 | 45 | 7.444 | Kansas - |
| 48 | | Al Hetrick | 334-95-4 | 77.598 | 1968-06 | 40 | 8.350 | Versailles OH - |
| 49 | | Luther Welsh | 333-180-6 | 64.740 | -2010 | 45 | 7.400 | Thomson - Retired 2010 |
| 49 | 22 | Joe Hamilton | 333-148-11 (5-4-0) | 68.801 | 1966-current | 46 | 7.239 | Blackhawk, PA PA: Midland, New Brighton, Hempfield - |
| 51 | | John Tucker | 332-132-10 | 71.097 | 1955-97 | 43 | 7.721 | Humboldt TN - |
| 52 | 23 | Vern Friedli | 331-159-6 (0-0-3) | 67.339 | 1962-current | 50 | 6.620 | Amphitheater Morenci, Casa Grande, San Manuel - |
| 53 | 24 | Jim Roth | 330-58-2 (14-1-0) | 84.872 | 1984-current | 28 | 11.786 | Southern Columbia Area - |
| 54 | 25 | Jack Johnson | 328-111-0 (5-6-0) | 74.715 | 1973-current | 39 | 8.410 | Great Falls C. M. Russell MT - |
| 54 | | Pat Panek | 328-117-29 | 72.257 | 1925-77 | 53 | 6.189 | Colorado - |
| 56 | | Jim Bellamy | 327-141-4 | 69.703 | 1960-2008 | 49 | 6.673 | Mt. Vernon, Schaller, West Liberty, Perry IA - |
| 57 | | Michael Pettine | 326-42-4 | 88.172 | 1967-99 | 33 | 9.879 | Pennsylvania - |
| 57 | 26 | T McFerrin | 326-101-4 (8-3-0) | 76.102 | 1968-82, 84, 86-96, 98-04, 09-current | 37 | 8.811 | Jefferson Georgia - |
| 57 | | Carl Madison | 326-139-7 | 69.809 | 1957-99, 2001-04 | 47 | 6.936 | Florida - |
| 60 | 27 | Tom Mach | 324-80-0 (12-2-0) | 80.198 | 1976-10 | 33 | 9.818 | Detroit Catholic Central - |
| 60 | | E. B. Etter | 324-102-13 | 75.285 | 1943-83 | 41 | 7.902 | Chattanooga TN - |
| 60 | 27 | Vincent O'Connor | 324-174-11 (5-5-0) | 64.735 | 1953-current | 59 | 5.492 | Fresh Meadows St. Francis NY - |
| 63 | | Dewey Sullivan | 323-80-2 | 80.000 | 1965-02 | 38 | 8.500 | Dayton OR - |
| 63 | | Pat Mancuso | 323-100-14 | 75.515 | 1955-96 | 42 | 7.690 | Ohio - |
| 65 | | Joe Tunnell | 322-137-7 | 69.850 | 1959-99 | 41 | 7.854 | Oklahoma - |
| 65 | | Armond Columbo | 322-103-9 | 75.230 | 1961-03 | 43 | 7.488 | Brockton, Archbishop Williams MA - |
| 67 | 29 | Bob Clayton | 320-74-1 (9-3-1) | 81.139 | -current | | | Heritage Hills - |
| 67 | | Dick Haines | 320-126-12 | 71.179 | 1952-94 | 43 | 7.442 | Ohio - |
| 67 | | Les Davis | 320-131-1 | 70.907 | 1959-current | 51 | 6.275 | Grenola, Greeley, Towanda Circle, Sedan KS - |
| 70 | 30 | Brent Steuerwald | 319-90-4 (11-1-0) | 77.724 | 1968-current | 44 | 7.250 | Shenendehowa NY - |
| 71 | 31 | Dwight Hochstetler | 318-106-1 (9-3-0) | 74.941 | 1978-current | 34 | 9.353 | Bowdon Greenville - |
| 71 | | Maurice Collins | 318-62-4 | 83.333 | 1960-88 1991-99 | 38 | 8.368 | DC - |
| 73 | | Bill Chappell | 317-74-9 | 80.375 | 1964-96 | 33 | 9.606 | Dalton - Retired 1996 |
| 73 | | Jimmy Moore | 317-105-5 | 74.824 | 1965-02 | 38 | 8.342 | Mississippi - |
| 75 | | Wayman Creel | 315-105-2 | 74.882 | 1952-89 | 38 | 8.289 | NorthsideAtlanta - Deceased 1990 |
| 76 | | Donald Howell | 314-73-2 | 80.977 | 1965-98 | 34 | 9.235 | Hobart, IN - |
| 77 | | Dick Dullaghan | 313-58-0 | 84.367 | 1969-79, 1984-03 | 31 | 10.097 | Indiana - |
| 77 | | Gene Cox | 313-99-4 | 75.721 | 1958-95 | 38 | 8.237 | Florida - |
| 77 | | Robert Paroli | 313-147-11 | 67.622 | 1959-99 | 41 | 7.634 | Westover, NC - |
| 77 | 32 | Ken Hofer | 313-141-2 (9-3-0) | 68.860 | 1964-71, 75-current | 45 | 6.956 | Menominee Stephenson - |
| 81 | 33 | Frank Lenti | 312-58-0 (9-4-0) | 84.324 | 1984-current | 28 | 11.143 | Mt. Carmel - |
| 82 | | August Bossu | 310-130-20 | 69.565 | 1948-53, 1955-93 | 45 | 6.889 | Cleveland Cathedral Latin, OH - |
| 83 | | Jesse Parker | 309-139-4 | 68.805 | | 39 | 7.923 | Camelback, Mesa Mountain View, Texas, Gilbert - |
| 83 | | Robert Holstead | 309-146-8 | 67.603 | 1955-68, 1970-95 | 40 | 7.725 | Tallulah, LA - |
| 83 | | Karl Kiefer | 309-138-3 | 69.000 | 1965-05 | 41 | 7.537 | McClintock, Phoenix Mountain Pointe, AZ - |
| 86 | | Walter Brooks | 308 | | 1936-74 | 39 | 7.897 | Hurricane, UT - |
| 86 | | Leo "Smokey" Boyd | 308-116-4 | 72.430 | 1953, 1956-99 | 45 | 6.844 | Saginaw Nouvel, MI - |
| 88 | | Robert Fairchild | 307-79-5 | 79.156 | 1960-97 | 38 | 8.079 | Chillicothe, MO - |
| 89 | | Don Bucci | 306-89-5 | 77.125 | 1966-99 | 34 | 9.000 | Youngstown Cardinal Mooney, OH - |
| 90 | | Bill Gentry | 305-102-5 | 74.636 | 1958-95 | 38 | 8.026 | Albuquerque Highland, NM - |
| 90 | | Mojo Hollowell | 305-187-7 | 61.824 | 1957-00 | 43 | 7.093 | Owensboro Catholic, KY - |
| 92 | | Jack Pratt | 304-129-7 | 69.886 | 1958-76, 80-06 | 44 | 6.909 | Flint St. Matthew, Grand Blanc - |
| 93 | | Nick Hyder | 302-48-5 | 85.775 | 1968-95 | 28 | 10.786 | Valdosta - Deceased 1996 |
| 93 | 34 | Rodney Walker | 302-150-3 (9-3-0) | 66.703 | 1970, 1972-current | 39 | 7.744 | MaryPersons SandyCreek - |
| 93 | | Glenn Daniel | 302-166-16 | 64.050 | 1946-92 | 47 | 6.426 | Pine Hill, AL - |
| 96 | | Bob Herring | 301-118-3 | 71.682 | -08 | | | Newnan (retired 2008) - |
| 96 | | Bruce Hendrickson | 301-172-2 | 63.579 | | | | Oklahoma - |
| 96 | | Norman Lineburg | 301-138-8 | 68.233 | 1970-03 | 34 | 8.853 | Radford, VA - |
| 96 | | Charles "Babe" Howell | 301-121-6 | 71.028 | 1966-00 | 35 | 8.600 | North Carolina - |
| 100 | | Conrad Nix | 300-108-1 | 73.472 | 1969-87, 94-2009 | 34 | 8.824 | NorthsideWR, FayetteCo, IrwinCo - Retired 2009 |
| 100 | | Walt Braun | 300-98-3 | 75.187 | 1956-98 | 43 | 6.977 | Marysville, MI - |
| 100 | | Bron Bacevich | 300-89-16 | 76.049 | 1930-74 | 45 | 6.667 | Michigan - |