| All-Time | Active | Coach | Record ('08) | Win% | Years | Seasons | Wins Per Season | School/Area |
| 1 | 1 | John McKissick | 601-148-13 (7-5-0) | 79.724 | 1952-current | 61 | 9.852 | Summerville - |
| 2 | 2 | John T. Curtis | 520-54-6 (14-0-0) | 90.172 | 1969-current | 44 | 11.818 | John Curtis - |
| 3 | 3 | Larry Campbell | 470-81-3 (11-2-0) | 85.108 | 1972-current | 41 | 11.463 | Lincoln County - |
| 4 | 4 | Mike Smith | 437-72-2 (9-3-0) | 85.714 | 1971-current | 42 | 10.405 | Hampton - |
| 5 | 5 | Corky Rogers | 426-73-1 (12-2-0) | 85.300 | 1968-current | 45 | 9.467 | The Bolles School, Jacksonville FL - |
| 6 | 6 | George Curry | 423-93-5 (10-2-0) | 81.670 | 1967-08, 12- | 44 | 9.614 | Berwick Wyoming Valley West, Berwick - |
| 6 | | G. A. Moore | 423-97-9 | 80.813 | 1962-04, 09-11 | 45 | 9.400 | Aubrey, Pilot Point - Retired 2011 |
| 8 | 7 | Al Fracassa | 416-117-7 (12-2-0) | 77.685 | 1963-current | 50 | 8.320 | Bloomfield Hills Brother Rice - |
| 9 | | Pete Atkins | 405-60-4 | 86.780 | 1951-94 | 45 | 9.000 | Missouri - |
| 10 | 8 | Bob Ladouceur | 400-24-3 (15-0-0) | 94.028 | 1979-current | 36 | 11.111 | Concord De La Salle, CA - |
| 10 | 8 | Dick Tighe | 400-155-8 (10-2-0) | 71.758 | 1954-current | 59 | 6.780 | St. Edmond, Fort Dodge - |
| 12 | | Gordon Wood | 396-91-15 | 80.378 | 1940-85 | 47 | 8.426 | Texas - |
| 13 | 10 | John Herrington | 392-92-1 (6-5-0) | 80.928 | 1970-current | 43 | 9.116 | Farmington Hill, Harrison MI - |
| 14 | 11 | Robert Hyland | 387-104-2 (13-0-0) | 78.702 | 1971-current | 42 | 9.214 | Fond du lac St Mary's Springs WI - |
| 15 | | Willie Varner | 383-132-10 | 73.905 | 1954-96 | 44 | 8.705 | Woodruff - |
| 16 | | Bob Lutz | 381-93-5 | 80.063 | 1969-05, 07-11 | 42 | 9.071 | Ironton St. Joe - Retired Jan. 2012 |
| 16 | | Ron Holtman | 381-103-8 | 78.252 | 1955-04 | 51 | 7.471 | Alton Marquette IL - |
| 18 | | Vic Paternostro | 373-67-5 | 84.382 | 1968-10 | 43 | 8.674 | Pope John - Passed away in 2012 |
| 19 | 12 | Curt Bladt | 372-42-0 (8-2-0) | 89.855 | 1978-current | 36 | 10.333 | Harlan IA - |
| 20 | | Joe Bradshaw | 371-120-4 | 75.354 | 1962-05 | 45 | 8.244 | Aliceville, AL - |
| 20 | 13 | Jerry Pezzetti | 371-140-1 (14-0-0) | 72.559 | 1968-current | 45 | 8.244 | Ankeny IA Mechler-Dallas, Murray, IA - |
| 20 | 13 | Jack Henzes | 371-153-8 (14-2-0) | 70.489 | 1960-current | 52 | 7.135 | Dunmore PA Wyoming Area - Coach at Dunmore since 1971 - Inducted into NHSACA Hall of Fame in 2009 |
| 23 | 15 | Larry (Bud) Wright | 370-162-2 (9-5-0) | 69.476 | 1968-current | | | Sheridan IN - |
| 24 | | Jerry Brewer | 368-105-2 | 77.684 | 1960-02 | 44 | 8.364 | Jasper - |
| 25 | | Frank McClellan | 367-77-4 | 82.366 | 1968-05 | 39 | 9.410 | Barton - |
| 26 | | Red Franklin | 366-76-8 | 82.222 | 1924-58 | 36 | 10.167 | Haynesville - |
| 27 | 16 | Jim Render | 364-118-7 (10-2-0) | 75.153 | 1970-current | 41 | 8.878 | Upper St Clair Uniontown PA, Carroliton OH - |
| 27 | | Howie Vogts | 364-124-10 | 74.096 | 1953-65, 67-09 | 56 | 6.500 | Bethpage NY - Deceased 2010 |
| 29 | 17 | Philip Haywood | 362-124-0 (12-3-0) | 74.486 | 1976-current | 38 | 9.526 | Belfry - |
| 30 | | Marijon Ancich | 361-137-4 | 72.311 | 1961-05, 2009-11 | 45 | 8.022 | St. Paul CA, Santa Fe Springs - Retired after 2011 season |
| 30 | | Elbert Wright | 361-126-17 | 73.313 | 1954-92 1994-99 | 46 | 7.848 | Texas - |
| 30 | 18 | Mike Boyd | 361-116-1 (9-3-0) | 75.628 | 1965-68, 70-current | 46 | 7.848 | Waterford Lady of the Lakes - |
| 30 | | Warren Wolf | 361-121-11 | 74.341 | 1958-08 | 52 | 6.942 | Brick - |
| 34 | | Terry Malone | 360-117-8 | 75.052 | 1956-03 | 49 | 7.347 | Hamilton Badin - |
| 35 | | Carlton Flatt | 354-68-1 | 83.806 | 1971-98 2002-06 | 34 | 10.412 | Brentwood Academy - |
| 36 | | Robert Davis | 353-73-1 | 82.787 | 1973-08 | 37 | 9.541 | WarnerRobins, Westside Macon - |
| 37 | | Duane Twait | 350-64-3 | 84.293 | 1964-02 | 40 | 8.750 | Emmetsburg IA - |
| 37 | | Dick Basham | 350-87-0 | 80.092 | 1970-09 | 41 | 8.537 | Milwaukee Marquette, WI - |
| 39 | | Dan Pitts | 346-109-4 | 75.817 | 1959-97 | 40 | 8.650 | MaryPersons - Retired 1997 |
| 39 | | Pinky Babb | 346-86-24 | 78.509 | 1935-81 | 48 | 7.208 | Greenwood SC - |
| 41 | | Dudley Hilton | 345-101-0 | 77.354 | | 35 | 9.857 | Bell County - |
| 41 | | Bob Schneider | 345-183-2 | 65.283 | 1966-09 | 44 | 7.841 | Newport Central Catholic KY - Retired January 2010 |
| 41 | | Jim Drewry | 345-158-5 | 68.406 | 1958-59, 1965-86, 1989-09 | 45 | 7.667 | Booneville MS - Retired after 2009 |
| 41 | 19 | Tom Stone | 345-100-1 (7-3-0) | 77.466 | 1967-current | 46 | 7.500 | Packwood Pekin, IA - |
| 45 | 20 | Frank Pazzaglia | 344-142-8 (4-6-0) | 70.445 | 1969-current | 44 | 7.818 | Mid Valley, PA - |
| 46 | | Tom Jaworski | 343-92-0 | 78.851 | 1972-10 | 39 | 8.795 | Creighton Prep - Retired after 2010 season |
| 47 | 21 | Jim Roth | 342-59-2 (12-1-0) | 85.112 | 1984-current | 29 | 11.793 | Southern Columbia Area - |
| 47 | | Rod Wotton | 342-94-3 | 78.246 | 1963-10 | 47 | 7.277 | Aquinas, Dover NH - |
| 49 | 22 | T McFerrin | 340-102-4 (14-1-0) | 76.682 | 1968-82, 84, 86-96, 98-04, 09-current | 38 | 8.947 | Jefferson Georgia - |
| 50 | | Herb Meyer | 338-150-14 | 68.725 | 1959-03 | 46 | 7.348 | Oceanside CA - |
| 51 | | Chris Geesman | 337-66-3 | 83.374 | 1965-02 | 39 | 8.641 | Mishawaka Penn IN - |
| 51 | 23 | Jack Johnson | 337-114-0 (9-3-0) | 74.723 | 1973-current | 40 | 8.425 | Great Falls C. M. Russell MT - |
| 51 | 23 | Ivan McGlone | 337-166-3 (6-5-0) | 66.897 | 1973-current | 41 | 8.220 | Russell Huntington Vinson WV - |
| 54 | 25 | Mike Glaser | 336-78-0 (8-5-0) | 81.159 | 1982-current | 31 | 10.839 | St. Xavier - |
| 54 | 25 | Joe Hamilton | 336-155-11 (3-7-0) | 68.028 | 1966-current | 47 | 7.149 | Blackhawk, PA PA: Midland, New Brighton, Hempfield - |
| 56 | | Edward Buller | 335-78-7 | 80.595 | 1940-84 | 46 | 7.283 | Kansas - |
| 57 | | Al Hetrick | 334-95-4 | 77.598 | 1968-06 | 41 | 8.146 | Versailles OH - |
| 58 | 27 | Tom Mach | 333-85-0 (9-5-0) | 79.665 | 1976-10 | 34 | 9.794 | Detroit Catholic Central - |
| 58 | | Luther Welsh | 333-180-6 | 64.740 | -2010 | 46 | 7.239 | Thomson - Retired 2010 |
| 60 | | John Tucker | 332-132-10 | 71.097 | 1955-97 | 44 | 7.545 | Humboldt TN - |
| 61 | | Vern Friedli | 331-159-6 | 67.339 | 1962-2011 | 50 | 6.620 | Amphitheater, Morenci, Casa Grande, San Manuel - Retired 2011 |
| 61 | 28 | Vincent O'Connor | 331-177-11 (7-3-0) | 64.836 | 1953-current | 60 | 5.517 | Fresh Meadows St. Francis NY - |
| 63 | | Pat Panek | 328-117-29 | 72.257 | 1925-77 | 54 | 6.074 | Colorado - |
| 64 | | Jim Bellamy | 327-141-4 | 69.703 | 1960-2008 | 50 | 6.540 | Mt. Vernon, Schaller, West Liberty, Perry IA - |
| 65 | 29 | Frank Lenti | 326-59-0 (13-1-0) | 84.675 | 1984-current | 29 | 11.241 | Mt. Carmel - |
| 65 | 29 | Sam Harp | 326-106-0 (9-4-0) | 75.463 | 1981-current | 32 | 10.188 | Danville - |
| 65 | | Michael Pettine | 326-42-4 | 88.172 | 1967-99 | 34 | 9.588 | Pennsylvania - |
| 65 | 29 | Dwight Hochstetler | 326-109-1 (8-3-0) | 74.885 | 1978-current | 35 | 9.314 | Bowdon Greenville - |
| 65 | | Carl Madison | 326-139-7 | 69.809 | 1957-99, 2001-04 | 48 | 6.792 | Florida - |
| 70 | | E. B. Etter | 324-102-13 | 75.285 | 1943-83 | 42 | 7.714 | Chattanooga TN - |
| 70 | 32 | Ken Hofer | 324-143-2 (11-2-0) | 69.296 | 1964-71, 75-current | 46 | 7.043 | Menominee Stephenson - |
| 72 | | Dewey Sullivan | 323-80-2 | 80.000 | 1965-02 | 39 | 8.282 | Dayton OR - |
| 72 | | Pat Mancuso | 323-100-14 | 75.515 | 1955-96 | 43 | 7.512 | Ohio - |
| 74 | | Joe Tunnell | 322-137-7 | 69.850 | 1959-99 | 42 | 7.667 | Oklahoma - |
| 74 | | Armond Columbo | 322-103-9 | 75.230 | 1961-03 | 44 | 7.318 | Brockton, Archbishop Williams MA - |
| 76 | | Bob Clayton | 320-74-0 | 81.218 | 1978-11 | 34 | 9.412 | Heritage Hills - Retired 2011 |
| 76 | | Dick Haines | 320-126-12 | 71.179 | 1952-94 | 44 | 7.273 | Ohio - |
| 76 | | Les Davis | 320-131-1 | 70.907 | 1959-current | 52 | 6.154 | Grenola, Greeley, Towanda Circle, Sedan KS - |
| 79 | | Brent Steuerwald | 319-90-4 | 77.724 | 1968-11 | 44 | 7.250 | Shenendehowa NY - |
| 80 | | Maurice Collins | 318-62-4 | 83.333 | 1960-88 1991-99 | 39 | 8.154 | DC - |
| 81 | | Bill Chappell | 317-74-9 | 80.375 | 1964-96 | 34 | 9.324 | Dalton - Retired 1996 |
| 81 | | Bob Redman | 317-115-0 | 73.380 | | 35 | 9.057 | Louisville Male - |
| 81 | | Jimmy Moore | 317-105-5 | 74.824 | 1965-02 | 39 | 8.128 | Mississippi - |
| 84 | | Gary Korhonen | 315-98-0 | 76.271 | 1964-65, 1972-07 | 38 | 8.289 | Elkader IA, Oak Lawn IL - Retired 2007 |
| 84 | | Wayman Creel | 315-105-2 | 74.882 | 1952-89 | 39 | 8.077 | NorthsideAtlanta - Deceased 1990 |
| 86 | | Donald Howell | 314-73-2 | 80.977 | 1965-98 | 35 | 8.971 | Hobart, IN - |
| 87 | | Dick Dullaghan | 313-58-0 | 84.367 | 1969-79, 1984-03 | 32 | 9.781 | Indiana - |
| 87 | | Gene Cox | 313-99-4 | 75.721 | 1958-95 | 39 | 8.026 | Florida - |
| 87 | | Robert Paroli | 313-147-11 | 67.622 | 1959-99 | 42 | 7.452 | Westover, NC - |
| 90 | 33 | Alan Chadwick | 311-55-0 (12-2-0) | 84.973 | 1985-current | 28 | 11.107 | Marist - |
| 91 | 34 | Ken Leonard | 310-67-0 (11-2-0) | 82.228 | 1984-current | 32 | 9.688 | Springfield (Sacred Heart-Griffin) Gridley - |
| 91 | | August Bossu | 310-130-20 | 69.565 | 1948-53, 1955-93 | 46 | 6.739 | Cleveland Cathedral Latin, OH - |
| 93 | 35 | Chuck Smith | 309-62-0 (9-4-0) | 83.288 | 1980-current | 33 | 9.364 | St. Mary's Colgan - |
| 93 | | Waldon Tucker | 309-126-3 | 70.890 | 1973-10 | 39 | 7.923 | Demopolis Acad - |
| 93 | | Jesse Parker | 309-139-4 | 68.805 | | 40 | 7.725 | Camelback, Mesa Mountain View, Texas, Gilbert - |
| 93 | | Robert Holstead | 309-146-8 | 67.603 | 1955-68, 1970-95 | 41 | 7.537 | Tallulah, LA - |
| 93 | | Karl Kiefer | 309-138-3 | 69.000 | 1965-05 | 42 | 7.357 | McClintock, Phoenix Mountain Pointe, AZ - |
| 98 | 36 | Rich Zinanni | 308-118-0 (5-4-0) | 72.300 | 1975-current | 38 | 8.105 | Kankakee (McNamara) - |
| 98 | | Walter Brooks | 308 | | 1936-74 | 40 | 7.700 | Hurricane, UT - |
| 98 | | Leo "Smokey" Boyd | 308-116-4 | 72.430 | 1953, 1956-99 | 46 | 6.696 | Saginaw Nouvel, MI - |
| 101 | | Robert Fairchild | 307-79-5 | 79.156 | 1960-97 | 39 | 7.872 | Chillicothe, MO - |
| 102 | | Don Bucci | 306-89-5 | 77.125 | 1966-99 | 35 | 8.743 | Youngstown Cardinal Mooney, OH - |
| 103 | 37 | Paul Moro | 305-50-0 (14-1-0) | 85.915 | 1984-current | 29 | 10.517 | Blue Ridge - |
| 103 | | Bill Gentry | 305-102-5 | 74.636 | 1958-95 | 39 | 7.821 | Albuquerque Highland, NM - |
| 103 | | Mojo Hollowell | 305-187-7 | 61.824 | 1957-00 | 44 | 6.932 | Owensboro Catholic, KY - |
| 106 | | Jack Pratt | 304-129-7 | 69.886 | 1958-76, 80-06 | 45 | 6.756 | Flint St. Matthew, Grand Blanc - |
| 107 | | Bob Lantzy | 303-115-1 | 72.434 | 1971-2011 | 41 | 7.390 | Utica Eisenhower - Retired 2011 |
| 108 | | Nick Hyder | 302-48-5 | 85.775 | 1968-95 | 29 | 10.414 | Valdosta - Deceased 1996 |
| 108 | | Rodney Walker | 302-150-3 | 66.703 | 1970, 1972-11 | 39 | 7.744 | Mary Persons, SandyCreek - Retired 2011 |
| 108 | | Glenn Daniel | 302-169-16 | 63.655 | 1946-92 | 48 | 6.292 | Pine Hill, AL - |
| 111 | | Bob Herring | 301-118-3 | 71.682 | -08 | | | Newnan (retired 2008) - |
| 111 | | Bruce Hendrickson | 301-172-2 | 63.579 | | | | Oklahoma - |
| 111 | | Norman Lineburg | 301-138-8 | 68.233 | 1970-03 | 35 | 8.600 | Radford, VA - |
| 111 | | Charles "Babe" Howell | 301-121-6 | 71.028 | 1966-00 | 36 | 8.361 | North Carolina - |
| 115 | | Bron Bacevich | 300-89-16 | 76.049 | 1933-49, 52-53 | 19 | 15.789 | Illinois - Retired 1953 |
| 115 | 38 | Chuck Kyle | 300-68-1 (11-2-0) | 81.436 | 1983-current | 30 | 10.000 | St. Ignatius - |
| 115 | | Conrad Nix | 300-108-1 | 73.472 | 1969-87, 94-2009 | 35 | 8.571 | NorthsideWR, FayetteCo, IrwinCo - Retired 2009 |
| 115 | | Matt Senffner | 300-114-1 | 72.410 | 1968-05 | 38 | 7.895 | New Lenox (Providence) - Retired 2005 |
| 115 | | Walt Braun | 300-98-3 | 75.187 | 1956-98 | 44 | 6.818 | Marysville, MI - |
| 115 | | Bron Bacevich | 300-89-16 | 76.049 | 1930-74 | 46 | 6.522 | Michigan - |